Endocrine Abstracts

Introduction: Aerobic (AER) and resistance (RES) exercise similarly improve HbA1c levels in type 2 diabetes subjects. However, it is still unknown whether exercise-induced acute changes in blood glucose differ according to exercise type. Our aim was to compare glucose level changes after a single bout of AER or RES exercise in trained diabetic subjects.Methods: Twenty-five subjects participating in the RAED2 Study, a RCT designed to compare the effects o...

We tested the hypothesis that common genetic variability of β cell mass and/or function genes may influence β cell functional mass in type 2 diabetes (T2DM). We studied 590 drug-naive GAD-negative patients with newly diagnosed T2DM (age: median=60.0 yrs; I.Q. range: 52–66; BMI: 29.3 kg/m2; 26.5–32.9). β cell functional mass was assessed by state-of-art mathematical modeling of glucose/C-peptide curves during a 240’ frequently sampled O...